Summary
This article reviews the case of a 19-year-old girl affected by Guillain-Barré syndrome since the age of 2 who presented at a clinic complaining for a chronic plantar hindfoot–infected ulceration. Serology showed increase of inflammatory markers and leukocytosis, and an MRI revealed osteomyelitis of calcaneum and soft tissue alterations with air bubbles. The patient was treated by an integrated multidisciplinary approach consisting of immediate admission, soft tissue and bone debridement, and administration of antibiotics under the close control of infectious disease specialist. After the control of acute condition, the patient underwent negative pressure therapy associated with instillation of antiseptic solution until the restoration of bone and soft tissue loss of substance and, eventually, to the application of bioactive glass substitute until the achievement of complete wound healing.
